Progression of primary acquired melanosis with atypia during pregnancy.

cone oil placement and onset of discomfort may be explained by long-term, slow leakage of silicone oil through the sclera. Free silicone oil within the extracellular matrix commonly causes a chronic granulomatous reaction that may lead to inflammation or functional impairment. Our patient described late development of ocular and orbital pain in a blind eye treated with silicone oil. Enucleation and orbital granuloma removal resolved the pain. It is important to consider extrascleral silicone oil granulomas in patients with ocular and orbital pain following treatment with silicone oil tamponade.